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Fertility irreversibly broken?   
I_am_THEdragon

I_am_THEdragon
Australia  


  2/9/2021

So I'm doing some gene editing with the Creatures 3 Genetics Lab from Creatures Unlimited, but it seems that whenever I make an edit to oestrogen or testosterone receptors or emitters, it irreversibly breaks the creature's sex drive functions, making them constantly produce libido lowerer and no estrogen/testosterone once they reach adulthood. Even changing them back to their original settings from before the break doesn't fix it and I have to start over.
I'm using the 2017 grendel genome as a base.

For context, I was making the grendel feel crowded when there's progesterone in her system, so that she isolates herself to lay the egg. I found that the effect stuck around for too long so I edited some genes to make the progesterone decay faster after laying the egg, as well as making the pregnancy last longer. This worked fine, but it made the female grendel able to breed again very quickly, and ideally I wanted this breed to reproduce at a lower rate than most other grendels. That's why I was editing the other reproductive genes, to make the grendels breed less frequently.

Anyone know why editing the hormone emitters and receptors irreveribly breaks them? Or if there's a way to fix it?

 
cyborg

cyborg



  2/12/2021

I have no experience with creatures’s D-DNA. Seriously I have no idea what is happening. I assume you’re frustrated with the lack of answers so I’ll take my best guess at least until Yomegami or Dragoler come back.

The Genetics Lab might bugged in that area? Maybe try Double’s Genetics Editor.

 
I_am_THEdragon

I_am_THEdragon
Australia  


  2/12/2021

That's my best guess too. I have only recently started learning D-DNA editing but I have a fairly good grasp on most of it, and I'm pretty sure that can't be right.

Well, the good news is that I have found a workaround. Instead of using the 2017 genome, I'm now using the CFF genome as a base, which already has breeding/fertility nerfed a bit. That, after all, was what I was going for when I kept breaking it. That said, I would still be grateful for any answers to what happened, especially in the case that anyone else encounters the same problem.

I've just had a look at Double's Genetics Editor, thanks for showing me! While I do prefer the more 'visual' interface of the Genetics Lab, I will consider switching if I have any other major issues.

 
ylukyun
Patient Pirate

ylukyun

Manager



  2/12/2021

Have you tried applying your edits to different base genomes? I'm curious to see if the same thing happens every time.
 


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